South America - Best4Cruises

Featured South America Cruises

Checkout our most popular cruises below.

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Ocean Cruises
45-Day Caribbean, South America & Scotia Arc Expedition
- Halifax, Nova Scotia
- 45 Nights
- 5 October 2026
- Seabourn
View Cruise: 45-Day Caribbean, South America & Scotia Arc Expedition
From:Prices on Request
Ocean Cruises
37-Day From The Caribbean To The Antarctic
- Bridgetown
- 41 Nights
- 13 October 2026
- Seabourn
View Cruise: 37-Day From The Caribbean To The Antarctic
From:Prices on Request
Ocean Cruises
From Panama’s wild beauty to Peruvian shores
- Colón
- 10 Nights
- 20 October 2026
- PONANT EXPLORATIONS
View Cruise: From Panama’s wild beauty to Peruvian shores
From:€5,419pp
Ocean Cruises
King George Island to King George Island
- King George Island, South Shetland Islands
- 6 Nights
- 20 October 2026
- Silversea
View Cruise: King George Island to King George Island
From:€16,649pp
Ocean Cruises
Puerto Williams to King George Island
- Puerto Williams
- 9 Nights
- 20 October 2026
- Silversea
View Cruise: Puerto Williams to King George Island
From:€9,849pp

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Popular Destinations

Checkout our most popular South America locations below.

Buenos Aires
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Callao
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Guayaquil
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King George Island, South Shetland Islands
View King George Island, South Shetland Islands
Lima
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Maceió
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